/*
 * TCMA site CSS stylesheet (global)
 * $Id$
 */

body {
    font-family: Arial, Helvetica, Sans-serif;
    margin: 0;
    padding: 0;
}

.invisible{
    display: none;
}

div.nav {
    position: absolute;
    top: 10px;
    left: 10px;
    width: 200px;
    color: black;
}

div.nav_menu {
    margin-top: 50px;
}

div.main_area {
    position: absolute;
    top: 0px;
    left: 210px;
    height: auto;
    width: 1000px;
    /*width: 850px; */
    color: black;
    padding-left: 10px;
}

div.main_content {
    border: 1px solid #C8C8C8;
    padding: 10px;
    margin-top: 20px;
    min-height: 400px;
}

/* MDACC Logo */
div.nav .logo img {
    width:  174px;
    height: auto;
    /* :TODO: Does not follow logo guidelines for margin. */
}

/* Mark the active navigation menu item */
.nav_menu > ul > li > a.active {
    color:           red     !important;
    pointer-events:  none    !important;
    text-decoration: none    !important;
}

#tcma_title h1 {
    display: inline;
}

#tcma_title {
    text-align: center;
    font-family: Sans-serif;
}

#gene_hits {
    border: solid 1px;
    margin-left: auto;
    margin-right: auto;
}

#gene_table {
    font-size: 0.9em;
    font-family: Arial, Helvetica, verdana sans-serif;
    background-color: #fff;
    border-collapse: collapse;
    width: 100%;
}

#gene_table thead td {
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
    color: #fff;
    padding: 2px;
    height: 25px;
    background-color: #074987;
    font-weight: normal;
    padding-left: 10px;
    padding-right: 10px;
}

tr.gene_table {
    height: 30px;
}

#gene_table tbody tr {
    background-color: #CBDCED;
    border-bottom: 1px solid #f0f0f0;
}

#gene_table tbody td {
    color: #414141;
    padding: 5px;
    padding-left: 10px;
    padding-right: 10px;
    text-align: left;
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
}

#gene_table tbody td a, tbody th a {
    color: #074987;
    text-decoration: underline;
    font-weight: normal; 
    display: block;
    background: transparent no-repeat 0% 50%;
}

#gene_table tbody td a:hover, tbody th a:hover {
    color: #009193;
    text-decoration: none;
}

#gene_table tr:nth-child(2n) {
    background-color: #99B7D3;
}

div.sub_title {
    background-color: #CBDCED;
    margin-bottom: 20px;
    margin-top: 10px;
    text-align: center;
}

span.fl {
    font-weight: bold;
    color: #074987;
}

#main_table th {
    /*background-color: #CBDCED;*/
    background-color: #E0AC4C;
    color: #FFFFFF;
}

#main_table tr {
    vertical-align: top;
}

#main_table .main_table_item {
    width: 30%;
    border: 1px solid #E0AC4C;
}

table p {
    text-align: justify;
}

.sub_table {
    border: 1px solid;
    padding: 2px;
}

td h3 {
    display: inline;
}

div.figure {
    border: 2px solid #C3D7FF;
    margin: 10px auto;
}

img.tutorial_main {
    width: 100%;
}

#search_hits_summary {
    text-align: right;
}
.hits_number {
    color: #118811;
}

#gene_info td {
    border: 1px solid;
    text-align: left;
    padding-left: 5px;
    padding-right: 5px;
}

#gene_info table {
    border-collapse: collapse;
    width: 100%;
}

#mutation_info td {
    text-align: left;
    padding-left: 5px;
    padding-right: 5px;
}

#summary table {
    width: 100%;
    border-collapse: collapse;
}

#computation table, #cell_survival table {
    width: 100%;
    border-collapse: collapse;
}

.nav-table td {
    border: none !important;
}

td.side_headers {
    font-weight: bold;
    text: #3790E4;
    width: 13%;
}

#mutation_info .side_headers {
    background-color: #BBD4E9;
}

#gene_info .side_headers {
    background-color: #9BB6D2;
}

#mutation_navigation_table {
    border-collapse: collapse;
}

#mutation_navigation_table td {
    border: none !important;
    text-align: center;
}

#external_resources ul {
    vertical-align: middle;
    margin: 0;
}

#external_resources li {
    margin-top: 5px;
}

span.ref_title {
    font-weight: bold;
}

textarea {
    resize: none;
}

#question_mark {
    border-width: 0;
}

.button {
    font-weight: bold;
}

.ui-tabs-nav {
    margin: 0;
    padding: .2em .2em 0;
    border: 1px solid;
}

.ui-tabs-nav li {
    list-style: none;
    float: left;
    margin: 0 .2em 1px 0;
    padding: .5em 1em;
    border-bottom: 0 !important;
}

.ui-tabs-nav li {
    list-style: none;
    float: left;
}

.ui-tabs {
    position: relative;
    padding: .2em;
    zoom: 1;
}

.ui-tabs .ui-tabs-nav {
    margin: 0;
    padding: .2em .2em 0;
}

.ui-tabs .ui-tabs-nav li {
    list-style: none;
    float: left;
    position: relative;
    top: 1px;
    margin: 0 .2em 1px 0;
    border-bottom: 0 !important;
    padding: 0;
    white-space: nowrap;
}

.ui-tabs .ui-tabs-nav li a {
    float: left;
    padding: .5em 1em;
    text-decoration: none;
}

.ui-tabs .ui-tabs-nav li.ui-tabs-selected {
    margin-bottom: 0; /*0*/
    padding-bottom: 0px;
}

.ui-tabs .ui-tabs-nav li.ui-tabs-selected a, .ui-tabs .ui-tabs-nav li.ui-state-disabled a, .ui-tabs .ui-tabs-nav li.ui-state-processing a {
    cursor: text;
}

.ui-tabs .ui-tabs-nav li a, .ui-tabs .ui-tabs-collapsible .ui-tabs-nav li.ui-tabs-selected a {
    cursor: pointer;
}

.ui-tabs .ui-tabs-panel {
    display: block;
    border-width: 0;
    padding: 1em 1.4em;
    background: none;
}

/* Corner radius */
.ui-corner-all, .ui-corner-top, .ui-corner-left, .ui-corner-tl {
    -moz-border-radius-topleft: 4px;
    -webkit-border-top-left-radius: 4px;
    -khtml-border-top-left-radius: 4px;
    border-top-left-radius: 4px;
}

.ui-corner-all, .ui-corner-top, .ui-corner-right, .ui-corner-tr {
    -moz-border-radius-topright: 4px;
    -webkit-border-top-right-radius: 4px;
    -khtml-border-top-right-radius: 4px;
    border-top-right-radius: 4px;
}

.ui-corner-all, .ui-corner-bottom, .ui-corner-left, .ui-corner-bl {
    -moz-border-radius-bottomleft: 4px;
    -webkit-border-bottom-left-radius: 4px;
    -khtml-border-bottom-left-radius: 4px;
    border-bottom-left-radius: 4px;
}

.ui-corner-all, .ui-corner-bottom, .ui-corner-right, .ui-corner-br {
    -moz-border-radius-bottomright: 4px;
    -webkit-border-bottom-right-radius: 4px;
    -khtml-border-bottom-right-radius: 4px;
    border-bottom-right-radius: 4px;
}

.ui-tabs-nav li a {
    display: block;
}

/* Component containers
----------------------------------*/
.ui-widget {
    font-family: Verdana,Arial,sans-serif;
    font-size: 0.5em;
}

.ui-widget .ui-widget {
    font-size: 0.5em;
}

.ui-widget input, .ui-widget select, .ui-widget textarea, .ui-widget button {
    font-family: Verdana,Arial,sans-serif;
    font-size: 0.5em;
}

.ui-widget-content {
    border: 1px solid #aaaaaa;
    background: #ffffff url(../images/ui-bg_glass_75_ffffff_1x400.png) 50% 50% repeat-x;
    color: #222222;
}

.ui-widget-content a {
    color: #222222;
}

.ui-widget-header {
    border: 1px solid #ffffff;
    background: #cccccc url(../images/ui-tabs-bg.png) 50% 50% repeat-x;
    color: #222222;
    font-weight: bold;
}

.ui-widget-header a {
    color: #222222;
}

/* Interaction states
----------------------------------*/

.ui-state-default a, .ui-state-default a:link, .ui-state-default a:visited {
    color: #555555;
    text-decoration: none;
}

.ui-state-hover, .ui-widget-content .ui-state-hover, .ui-widget-header .ui-state-hover, .ui-state-focus, .ui-widget-content .ui-state-focus, .ui-widget-header .ui-state-focus {
    border: 1px solid #999999;
    background: #dadada url(../images/ui-bg_glass_75_dadada_1x400.png) 50% 50% repeat-x;
    color: #212121;
    font-weight: normal;
}

.ui-state-hover a, .ui-state-hover a:hover {
    color: #212121;
    text-decoration: none;
}

.ui-state-active, .ui-widget-content .ui-state-active, .ui-widget-header .ui-state-active {
    border: 1px solid #aaaaaa;
    background: #ffffff url(../images/ui-bg_glass.png) 50% 50% repeat-x;
    font-weight: normal;
    color: #212121;
}

.ui-state-active a, .ui-state-active a:link, .ui-state-active a:visited {
    color: #212121;
    text-decoration: none;
}

.ui-widget :active {
    outline: none;
}

.ui-state-default a {
    font-size: 0.72em;
}

#mutation_table td {
    border: 1px solid;
}

#pre_fun_imp_table table {
    border-collapse: separate !important;
}

#pre_fun_imp_table td, #pre_fun_imp_table th{
    border: none;
    background: #D9D9DD;
    color: #515151;
    text-align: center;
}

#pre_fun_imp_table .imp_high {
    background-color: #C83C3C;
}

#pre_fun_imp_table .imp_medium {
    background-color: #C79060;
}

#pre_fun_imp_table .imp_low {
    background-color: #C8C864;
}

#pre_fun_imp_table .imp_neutral {
    background-color: #FFFFFF;
}

div.imp_high {
    alignment-adjust: auto;
    width: 50px;
    margin: auto;
    text-align: center;
    color: #000000;
}

#pre_fun_imp_table th {
    font-weight: bold;
}

#rppa_table {
    font-size: 0.9em;
    font-family: Arial, Helvetica, verdana sans-serif;
    background-color: #fff;
    border-collapse: collapse;
    width: 100%;
}

#rppa_table thead td {
    border-right: 1px solid #FFFFFF;
    border-left: 1px solid #FFFFFF;
    border-bottom: 1px solid #FFFFFF;
    color: #FFFFFF;
    padding: 2px;
    height: 25px;
    background-color: #074987;
    font-weight: normal;
    padding-left: 10px;
    padding-right: 10px;
}

tr.rppa_table {
    height: 30px;
}

#rppa_table tbody tr {
    background-color: #FFFFFF;
    border-bottom: 1px solid #f0f0f0;
}

#rppa_table tbody td {
    color: #414141;
    padding: 5px;
    padding-left: 10px;
    padding-right: 10px;
    text-align: left;
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
}

#rppa_table tbody td a, tbody th a {
    color: #074987;
    text-decoration: underline;
    font-weight: normal; 
    display: block;
    background: transparent no-repeat 0% 50%;
}

#rppa_table tbody td a:hover, tbody th a:hover {
    color: #009193;
    text-decoration: none;
}

#rppa_table .odd {
    background-color: #CBDCED;
}

#rppa_table .even {
    background-color: #99B7D3;
}

.details_open {
    background-image: url("../images/details_open.png");
    background-repeat: no-repeat;
    height: 20px;
    width: 20px;
}

.details_close {
    background-image: url("../images/details_close.png");
    background-repeat: no-repeat;
    height: 20px;
    width: 20px;
}

#drug_table {
    font-size: 0.9em;
    font-family: Arial, Helvetica, verdana sans-serif;
    background-color: #fff;
    border-collapse: collapse;
    width: 100%;
}

#drug_table thead td {
    border-right: 1px solid #FFFFFF;
    border-left: 1px solid #FFFFFF;
    border-bottom: 1px solid #FFFFFF;
    color: #FFFFFF;
    padding: 2px;
    height: 25px;
    background-color: #074987;
    font-weight: normal;
    padding-left: 10px;
    padding-right: 10px;
}

tr.drug_table {
    height: 30px;
}

#drug_table tbody tr {
    background-color: #FFFFFF;
    border-bottom: 1px solid #f0f0f0;
}

#drug_table tbody td {
    color: #414141;
    padding: 5px;
    padding-left: 10px;
    padding-right: 10px;
    text-align: left;
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
}

#drug_table tbody td a, tbody th a {
    color: #074987;
    text-decoration: underline;
    font-weight: normal; 
    display: block;
    background: transparent no-repeat 0% 50%;
}

#drug_table tbody td a:hover, tbody th a:hover {
    color: #009193;
    text-decoration: none;
}

#drug_table tr:nth-child(2n+1) {
    background-color: #CBDCED;
}

#drug_table tr:nth-child(2n) {
    background-color: #99B7D3;
}

.table-striped {
    font-size: 0.9em;
    font-family: Arial, Helvetica, verdana sans-serif;
    background-color: #fff;
    border-collapse: collapse;
    width: 100%;
}

.table-striped tr{
    height: 30px;
}

.table-striped tr:nth-child(2n+1) {
    background-color: #CBDCED;
}

.table-striped tr:nth-child(2n) {
    background-color: #99B7D3;
}

.table-striped thead th {
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
    color: #fff;
    padding: 2px;
    height: 25px;
    background-color: #074987;
    font-weight: normal;
    padding-left: 10px;
    padding-right: 10px;
}

.table-striped tbody tr {
    background-color: #CBDCED;
    border-bottom: 1px solid #f0f0f0;
}

.table-striped tbody td {
    color: #414141;
    padding: 5px;
    padding-left: 10px;
    padding-right: 10px;
    text-align: left;
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
}

.table-striped tbody td a, tbody th a {
    color: #074987;
    text-decoration: underline;
    font-weight: normal; 
    display: block;
    background: transparent no-repeat 0% 50%;
}

.table-striped tbody td a:hover, tbody th a:hover {
    color: #009193;
    text-decoration: none;
}

.drug_structure {
    background: #FFFFFF !important;
}

#drug_sensitivity_table {
    font-size: 0.9em;
    font-family: Arial, Helvetica, verdana sans-serif;
    background-color: #fff;
    border-collapse: collapse;
    width: 100%;
}

#drug_sensitivity_table thead td {
    border-right: 1px solid #FFFFFF;
    border-left: 1px solid #FFFFFF;
    border-bottom: 1px solid #FFFFFF;
    color: #FFFFFF;
    padding: 2px;
    height: 25px;
    background-color: #074987;
    font-weight: normal;
    padding-left: 10px;
    padding-right: 10px;
}

tr.drug_sensitivity_table {
    height: 30px;
}

#drug_sensitivity_table tbody tr {
    background-color: #FFFFFF;
    border-bottom: 1px solid #f0f0f0;
}

#drug_sensitivity_table tbody td {
    color: #414141;
    padding: 5px;
    padding-left: 10px;
    padding-right: 10px;
    text-align: left;
    border-right: 1px solid #fff;
    border-left: 1px solid #fff;
}

#drug_sensitivity_table tbody td a, tbody th a {
    color: #074987;
    text-decoration: underline;
    font-weight: normal; 
    display: block;
    background: transparent no-repeat 0% 50%;
}

#drug_sensitivity_table tbody td a:hover, tbody th a:hover {
    color: #009193;
    text-decoration: none;
}

#drug_sensitivity_table .odd {
    background-color: #CBDCED;
}

#drug_sensitivity_table .even {
    background-color: #99B7D3;
}

.details_open {
    background-image: url("../images/details_open.png");
}

.details_close {
    background-image: url("../images/details_close.png");
}

.literature_summary {
    font-weight: bold;
}

#mutaiton_summary table {
    width: 100%;
    border-collapse: collapse;
    border: 1px solid;
}

#mutation_summary td {
    text-align: left;
    padding-left: 5px;
    padding-right: 5px;
    border: 1px solid;
}

#mutation_summary_table td {
    border: 1px solid;
    border-collapse: collapse;
}

#mutation_summary_table {
    border: 1px solid;
    border-collapse: collapse;
}

#mutation_summary .side_headers {
    background-color: #BBD4E9;
}

#pre_fun_imp_table td {
    border-collapse: collapse;
}

#mutation_if_table table {
    border: 1px solid;
    border-collapse: collapse;
}

#literature_table {
    background-color: #CBDCED;
}

.footer {
    text-align: center;
    font-size: small;
}

/* Suggest results */
ul.suggest-dropdown {
    border: 1px solid #999;
    background-color: #eee;
    padding: 0;
    margin: 0;
    list-style: none;
    opacity: .85;
    -moz-box-shadow: 2px 2px 10px #333;
    -webkit-box-shadow: 2px 2px 10px #333;
}

ul.suggest-dropdown li {
    color: #101010;
    padding: 2px 5px;
    text-align: left;
    white-space: nowrap;
}

ul.suggest-dropdown li.selected {
    background: Highlight;
    color: HighlightText;
    cursor: pointer;
}

/* Nav arrow image and text*/
.nav_arrow_img {
    width: 20px;
    height: 20px;
}

.nav_arrow_img_box {
    border: 1px solid;
    width:  70px;
    height: 30px;
    background-image: url('../images/nav_arrow_5.png');
    background-size: 20px 20px;
    background-repeat: no-repeat;
    background-position: right;
}

.nav_arrow_img_text {
    text-align: left;
    margin: 0;
    padding-left: 12px;
    padding-top: 13px;
    font-size: 50%;
    color: #0180FF;
}

.nav_arrow a{
    text-decoration: none;
}

.breadCrumbHolder {
    margin: 0 0 20px 0;
}

pre {
    background: #ddd;
    border: solid 1px #fff;
    padding: 10px;
    color: #111;
}

.description {
    float: left;
    width: 700px;
    margin-right: 20px;
}

.sideBar {
    float: left;
    background: #fff;
    border: solid 1px #dedede;
    padding: 20px;
    width: 238px;
    margin: 50px 0 0 0;
}

.license p {
    font-size: 0.83333em;
    color: #888;
}

/*#breadCrumb {
    background-image: url("../images/breadcrumb_nav_bg.gif");
}*/

.datagrid table {
    border-collapse: collapse;
    text-align: left;
    width: 100%;
}

.datagrid {
    font: normal 12px/150% Arial, Helvetica, sans-serif;
    background: #fff;
    overflow: hidden;
    border: 1px solid #006699;
    -webkit-border-radius: 3px;
    -moz-border-radius: 3px;
    border-radius: 3px;
}

.datagrid table td, .datagrid table th {
    padding: 3px 10px;
}

.datagrid table thead th {
    background: -webkit-gradient( linear, left top, left bottom, color-stop(0.05, #006699), color-stop(1, #00557F) );
    background: -moz-linear-gradient( center top, #006699 5%, #00557F 100% );
    filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#006699', endColorstr='#00557F');
    background-color: #006699;
    color: #FFFFFF;
    font-size: 15px;
    font-weight: bold;
    border-left: 1px solid #0070A8;
}

.datagrid table thead th:first-child {
    border: none;
}

.datagrid table tbody td {
    color: #00496B;
    border-left: 1px solid #E1EEF4;
   font-size: 12px;
   font-weight: normal;
}

.datagrid table tbody .alt td {
    background: #E1EEF4;
    color: #00496B;
}

.datagrid table tbody td:first-child {
    border-left: none;
}

.datagrid table tbody tr:last-child td {
    border-bottom: none;
}

.datagrid table tfoot td div {
    border-top: 1px solid #006699;
    background: #E1EEF4;
}

.datagrid table tfoot td {
    padding: 0;
    font-size: 12px;
}

.datagrid table tfoot td div {
    padding: 2px;
}

.datagrid table tfoot td ul {
    margin: 0;
    padding: 0;
    list-style: none;
    text-align: right;
}

.datagrid table tfoot  li {
    display: inline;
}

.datagrid table tfoot li a {
    text-decoration: none;
    display: inline-block;
    padding: 2px 8px;
    margin: 1px;
    color: #FFFFFF;
    border: 1px solid #006699;
    -webkit-border-radius: 3px;
    -moz-border-radius: 3px;
    border-radius: 3px;
    background: -webkit-gradient( linear, left top, left bottom, color-stop(0.05, #006699), color-stop(1, #00557F) );
    background: -moz-linear-gradient( center top, #006699 5%, #00557F 100% );
    filter:progid:DXImageTransform.Microsoft.gradient(startColorstr='#006699', endColorstr='#00557F');
    background-color: #006699;
}

.datagrid table tfoot ul.active, .datagrid table tfoot ul a:hover {
    text-decoration: none;
    border-color: #006699;
    color: #FFFFFF;
    background: none;
    background-color: #00557F;
}

#control_area {
    font-size: small;
}

.help_section {
    background-image: url('../images/information.png');
    background-size: 25px 25px;
    background-repeat: no-repeat;
    background-position: 10px 10px;
    padding: 10px 10px 10px 50px;
    margin-left: 0px;
    margin-top: 5px;
    background-color: #EFFAED;
    border: 1px solid #339F2A;
    -moz-border-radius: 10px;
    border-radius: 10px;
    color: #339F2A;
}

.info_section {
    background-image: url('../images/information.png');
    background-size: 25px 25px;
    background-repeat: no-repeat;
    background-position: 10px 10px;
    padding: 10px 10px 10px 50px;
    margin-left: 0px;
    margin-top: 5px;
    background-color: #EFFAED;
    border: 1px solid #339F2A;
    -moz-border-radius: 10px;
    border-radius: 10px;
    color: #339F2A;
}

.warning_section {
    background-image: url('../images/warning.png');
    background-size: 25px 25px;
    background-repeat: no-repeat;
    background-position: 10px 10px;
    padding: 10px 10px 10px 50px;
    margin-left: 0px;
    margin-top: 5px;
    background-color: #FFECED;
    border: 1px solid #FBB3B9;
    -moz-border-radius: 10px;
    border-radius: 10px;
    color: #f0051e;
}

img {
    border-style: none;
}

p.prereq {
    color: red;
}

.dontsueus {
    font-weight: bold;
}

img.table_help {
    width: 15px;
    height: 15px;
}

#network_legend td{
    padding-bottom: 1em;
}

#network_control td{
    padding-bottom: 1em;
}

p {
    text-align: justify;
}

tfoot input.search_init {
    color: #999999;
}

.hide {
    display: none;
}
